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As part of their research, they have put together a set of proposed improvements for Node.js' Web streams implementation that will eliminate promises in certain code paths which can yield a significant performance boost up to 10x faster, which only goes to prove the point: promises, while useful, add significant overhead. As one of the core maintainers of Node.js, I am looking forward to helping Malte and the folks at Vercel get their proposed improvements landed!

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This anomaly is indicative of the larger challenge of culturing various microbial species, referred to as microbial “unculturability.” This cannot be explained by the use of agar alone or by the substitution of an alternative gelling agent, but rather by the difficulties in consistently recreating on an agar plate the multi-variable environment in which microbes grow naturally. Given such challenges, the risk of shortages, and the vulnerabilities of the agar supply chain, why is it so difficult to find suitable alternatives?

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